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research-review:aging-converts-innate-b1a-cells-into-potent-cd8-t-cell-inducers
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Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers
Lee-Chang C, Bodogai M, Moritoh K, et al. Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers. J Immunol. 2016;196(8):3385-3397. doi:10.4049/jimmunol.1502034
This article will be discussed on November 14th at Biotech without Borders as part of the Deep Dive series.
Abstract (tldr;)
Materials and methods
Flow cytometry
Labelling
Sorting/Detection
In vitro stimulation
In vivo antigen specific stimulation
Results
Aging milieu activated B1a cells
Aging converts B1a cells into 4BL cells
Myeloid cells induce the generate of 4BL cells that drive antigen specific cytotoxic effects
Putative mechanism of myeloid induction
Discussion
research-review/aging-converts-innate-b1a-cells-into-potent-cd8-t-cell-inducers.1572883986.txt.gz · Last modified: 2019/11/04 16:13 by danny
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