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news-review:tick-tock-dna-methylation-the-epigenetic-clock-and-exceptional-longevity [2019/08/03 23:05] marcos [Epigenetic Clocks & Interpretation of Data] |
news-review:tick-tock-dna-methylation-the-epigenetic-clock-and-exceptional-longevity [2019/08/05 23:20] (current) marcos [Abstract] |
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- | With the advancement in science and technology, many clues are available, but not enough to have a clear picture of the cause of aging, or the traits of individuals that live long healthy lives. Scientists have not succeeded in discovering genes associated with exceptional longevity. Attempts have been made to find other genome attributes that lead to longevity, besides genes or other DNA sequences. | + | With the advancement in science and technology, many clues are available, but not enough to have a clear picture of the cause of aging, or the genomic traits of individuals that will live long healthy lives. Scientists have not succeeded in discovering genes associated with exceptional longevity. Attempts have been made to find other genome attributes that lead to longevity, besides genes or other DNA sequences. |
DNA does not live in a void by itself. Kwok et al overview studies pertaining to molecules that attach to DNA. In particular, studies of [[https://www.nature.com/scitable/topicpage/the-role-of-methylation-in-gene-expression-1070 |DNA methylation]], the adding of methyl groups to a cytosine base of DNA. Methylation can change the activity of molecular interactions with a DNA segment. | DNA does not live in a void by itself. Kwok et al overview studies pertaining to molecules that attach to DNA. In particular, studies of [[https://www.nature.com/scitable/topicpage/the-role-of-methylation-in-gene-expression-1070 |DNA methylation]], the adding of methyl groups to a cytosine base of DNA. Methylation can change the activity of molecular interactions with a DNA segment. |